Current Thoracic Surgery

Nodular ganglioneuroblastoma is an exceptionally rare neuroblastic neoplasm in the adult population. This report details a highly unusual case of posterior mediastinal ganglioneuroblastoma in a 55-year-old male who presented solely with posterior chest pain. Radiological investigations, including computed tomography and magnetic resonance imaging, demonstrated an encapsulated, highly cellular tumor in the left costovertebral groove at the D7 level, with no evidence of distant metastasis on positron emission tomography. The patient underwent successful surgical resection following preoperative embolization and experienced an uneventful postoperative recovery. Histopathological analysis confirmed the diagnosis of nodular ganglioneuroblastoma. In summary, ganglioneuroblastoma should be considered in the differential diagnosis of posterior mediastinal tumors, even in adult patients.