Current Thoracic Surgery 2020 , Vol 5 , Issue 2
Intrapleural tranexamic acid in persistent malignant hemothorax: a case report
Özgür Öztürk1,Demet Yaldız2,Arkın Acar3,Kenan Can Ceylan3,Şeyda Örs Kaya3,Funda Cansun3
1Department of Thoracic Surgery, University Of Health Sciences, Tepecik Training and Research Hospital, İzmir, Turkey
2Department of Thoracic Surgery, Manisa Celal Bayar University, Faculty of Medicine, Manisa, Turkey
3Department of Thoracic Surgery, University of Health Sciences, Dr. Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital, İzmir, Turkey
DOI : 10.26663/cts.2020.00017 Viewed : 3655 - Downloaded : 1784 Hemothorax occurs due to various conditions such as trauma, malignancy, tuberculosis, bullous lung disease, and lung abscess. In patients with malignant hemothorax, stabilization of the clinical condition and treatment of primary disease is of primary importance. A 53-year-old female patient, who had a history of surgery for ovarian cancer and liver metastasis, admitted to the hospital with complaints of shortness of breath. The patient was found to have pleural effusion on the right hemithorax, and a tube thoracostomy was performed. During the clinical follow-up, the amount of drainage did not decrease. Thereby, the patient underwent a video-thoracoscopic evaluation, and chemical pleurodesis was applied intraoperatively. Despite chemical pleurodesis, hemorrhagic drainage continued. Intrapleural tranexamic acid administration was performed to ensure the stabilization of the clinical condition. Immediately days after the intrapleural application of tranexamic acid, the drainage of the fluid decreased and became sero-hemorrhagic. The management of this case made us think that intrapleural tranexamic acid may be an alternative in persistent malign hemothorax. Keywords : tranexamic acid, malign effusion, pleura, hemothorax