Current treatment options for post-thoracotomy pain syndrome: a review
Elif Yakşi1,Osman Yakşi2
Current Thoracic Surgery
2017;2(3):103-110. (27 December 2017)
1Department of Physical Medicine and Rehabilitation, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, Istanbul, Turkey
2Department of Chest Surgery, Düzce Faculty of Medicine, Düzce, Turkey
DOI :
10.26663/cts.2017.0020
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Thoracotomy is one of the most painful surgical procedures known. Chronic pain in the postoperative
period after thoracotomy is a common complication. Post-thoracotomy pain syndrome (PTPS) is a
chronic pain with neuropathic and non-neuropathic components, continuing after 2 months of
thoracotomy, causing disability by affecting the daily activities and functions of patients. Patients
generally describe neuropathic symptoms such as hyperalgesia, allodynia, hypoesthesia at the site of
the incision or related dermatomes. Etiology includes preoperative, intraoperative and postoperative
factors. Although the mechanism of PTPS formation is not clear yet, the most common cause is the
intercostal nerve injury. PTPS treatment is complex because of the neuropathic component of the pain.
The risk of PTPS formation can be reduced by controlling early pain before the onset of the disease.
When pain occurs, medical treatments are implemented and also minimally invasive interventional
procedures could be performed if necessary.
Keywords :
Thoracotomy, Chronic pain, Neuropathic pain